Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5224572 | Tetrahedron | 2008 | 13 Pages |
Abstract
Several novel 2-alkylamino- and 2-alkylthiothiazolo[5,4-e]- and -[4,5-g]indazoles and their 6-alkyl and 8-alkyl derivatives have been synthesised in high overall yields starting from 5-nitro and 6-nitroindazoles in a three-step route involving the regioselective cyclisation of thioureidoindazoles and indazolyl dithiocarbamates as the key steps. Some assorted thiazoloindazoles have been screened for anticancer properties, which demonstrated the anticancer potential of at least one product, justifying its further follow-up.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Manas Chakrabarty, Taraknath Kundu, Shiho Arima, Yoshihiro Harigaya,