Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5224615 | Tetrahedron | 2010 | 8 Pages |
Abstract
An intramolecular Ugi 5-centre-4-component reaction (U-5C-4CR) followed by a palladium-catalysed ring-opening has been employed to transform oxabicycloheptene-based β-amino acids into two families of regioisomeric polyfunctionalised cyclohexenols. The whole process is completely stereoselective and enantiomerically pure products are obtained in high overall yields.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Andrea Basso, Luca Banfi, Giuseppe Guanti, Renata Riva,