Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5224616 | Tetrahedron | 2010 | 6 Pages |
Abstract
4-Amino-3,5-dihalopyridines have been efficiently prepared via microwave-assisted nucleophilic aromatic substitution of 3,4,5-trihalopyridines using 1-1.1Â equiv of primary and secondary amines. The reaction is also applicable to electron rich arylamines.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Mark Pichowicz, Simon Crumpler, Edward McDonald, Julian Blagg,