Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5224686 | Tetrahedron | 2009 | 6 Pages |
Abstract
Chan's diene proved to react with aromatic aldehydes under organocatalytic conditions in presence of a chiral naphthyl-TADDOL derivative to give vinylogous aldols (up to 65% ee) with complete γ-selectivity. A further process of hetero-Diels-Alder cycloaddition, leading to chiral pyran-4-one derivatives (up to 60% ee), was favoured by electron-withdrawing substituents on the aromatic ring.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Rosaria Villano, Maria Rosaria Acocella, Antonio Massa, Laura Palombi, Arrigo Scettri,