| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5224733 | Tetrahedron | 2008 | 5 Pages |
Abstract
Chiral phosphine oxides (Lewis bases) catalyze silicon tetrachloride-mediated, enantioselective phosphonylation of aldehydes with trialkyl phosphites (Abramov-type reaction), which leads to optically active α-hydroxyphosphonates with moderate enantioselectivities. 31P NMR analysis of the phosphonylation of benzaldehyde with triethyl phosphite supports the assumed reaction mechanism.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Kyoko Nakanishi, Shunsuke Kotani, Masaharu Sugiura, Makoto Nakajima,