Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5224826 | Tetrahedron | 2009 | 6 Pages |
Abstract
The homocoupling reaction between the conjugated n-(2-chloroethenyl)pyridine; n, 2-, 3- and 4- (or quinoline; n, 2- and 4-) mediated by zero-valent nickel complexes at room temperature affords to the corresponding 1,4-diaryl-1,3-butadiene, always as the 1E,3E stereoisomer. The yield in 1,4-diaryl-1,3-butadiene increases with the nickel catalyst and hence, the active zero-valent nickel catalyst is not regenerated during the homocoupling reaction.The stereospecific synthesis of (1Z,3Z)-1,4-di(4â²-pyridyl)-1,3-butadiene stereoisomer was efficiently carried out by partial hydrogenation of the appropriate 1,4-di(4â²-pyridyl)-1,3-butadiyne.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
J.G. RodrÃguez, Cristina DÃaz-Oliva,