Article ID Journal Published Year Pages File Type
5224912 Tetrahedron 2009 5 Pages PDF
Abstract

A protective group free, concise, and stereoselective total synthesis of (+)-artemisinin, starting from readily available (R)-(+)-citronellal, is described. Asymmetric 1, 4-addition, Aldol condensation, Ene reaction, regioselective hydroboration are the key steps involved in the total synthesis of the target molecule.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry