| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5224946 | Tetrahedron | 2009 | 5 Pages |
Abstract
Isoquinoline reacts smoothly with aroylnitromethanes in the presence of dialkyl acetylenedicarboxylates and dibenzoylacetylene to produce pyrrolo[2,1-a]isoquinolines in good yields. Quinoline and benzothiazole also react in a similar way. Pyridine and N-methylimidazole catalyze the reaction between nitromethane derivatives with electron-deficient acetylenes to produce highly functionalized isoxazoles.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
![Synthesis of pyrrolo[2,1-a]isoquinolines from activated acetylenes, benzoylnitromethanes, and isoquinoline](/preview/png/5224946.png "First Page Preview: Synthesis of pyrrolo[2,1-a]isoquinolines from activated acetylenes, benzoylnitromethanes, and isoquinoline")
Authors
Issa Yavari, Mohammad Piltan, Loghman Moradi,