| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5225224 | Tetrahedron | 2007 | 6 Pages |
Abstract
We report an efficient one-step approach to 4-thio and 4-aminopyrrolo[3,4-c]pyridines based on the selective reaction of malonthioamides and malonamidines with methyl acetylpyruvate. Structural proof is given by HMBC and HMQC spectra. A cascade heterocyclization mechanism is proposed for the reactions studied.
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Organic Chemistry
![Reactions of malonthioamides and malonamidines with methyl acetylpyruvate as a one-step method to prepare 4-thio- and 4-aminopyrrolo[3,4-c]pyridines](/preview/png/5225224.png "First Page Preview: Reactions of malonthioamides and malonamidines with methyl acetylpyruvate as a one-step method to prepare 4-thio- and 4-aminopyrrolo[3,4-c]pyridines")
Authors
Vera S. Berseneva, Vasiliy A. Bakulev, Wim Dehaen, Suzanne Toppet, Marina Borovkova,