| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5225267 | Tetrahedron | 2007 | 11 Pages |
Abstract
We report the synthesis of Fmoc protected single amino acid chelates (SAAC) and their metal complexes. The modified amino acids are suitable for solid-phase peptide synthesis. The use of 4-hydroxymethylbenzoic acid AM (HMBA-AM) resin allows the nucleophilic cleavage of the peptide-metal complexes from the resin without decomplexation.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Georg Dirscherl, Robert Knape, Paul Hanson, Burkhard König,