Article ID Journal Published Year Pages File Type
5225281 Tetrahedron 2007 6 Pages PDF
Abstract

The steric hindrance of the 7α-OR group in bile acid derivatives is very different from the 12α-OR group. The effect of this difference in steric hindrance on the synthesis of cyclocholates has been evaluated with support from AM1 and MM2 calculations. The 13C NMR parameters for cheneodeoxycholic acid-based cyclocholates have been determined.

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Physical Sciences and Engineering Chemistry Organic Chemistry
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