Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5225281 | Tetrahedron | 2007 | 6 Pages |
Abstract
The steric hindrance of the 7α-OR group in bile acid derivatives is very different from the 12α-OR group. The effect of this difference in steric hindrance on the synthesis of cyclocholates has been evaluated with support from AM1 and MM2 calculations. The 13C NMR parameters for cheneodeoxycholic acid-based cyclocholates have been determined.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
H.R. Ferhat Karabulut, Suad A. Rashdan, Jerry Ray Dias,