| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5225393 | Tetrahedron | 2007 | 6 Pages |
Abstract
The natural flavors 2-acetyl-1-pyrroline 1a, 2-propionyl-1-pyrroline 1b, 2-acetyl-3,4,5,6-tetrahydropyridine 1c, 2-acetyl-2-thiazoline 1d, 2-propionyl-2-thiazoline 1e, and the artificial flavor 2-acetyl-5,6-dihydro-4H-1,3-thiazine 1f have been prepared by catalytic SeO2 oxidation of the corresponding cyclic imines 6a-c and sulfur cyclic imines 7a-c using TBHP as co-oxidant. The oxidation of the pyrrolines 1a and b is completely regioselective. Professional olfactory evaluation together with the odor threshold of the new flavor 1f is reported.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Claudio Fuganti, Francesco G. Gatti, Stefano Serra,