| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5225431 | Tetrahedron | 2009 | 6 Pages |
Abstract
An efficient and novel organocatalyst has been developed for the asymmetric desymmetrization of meso- and prochiral ketones by direct Michael addition to nitroolefins. This strategy can afford the desymmetrization products with excellent diastereo- (up to >99:1) and enantioselectivity (up to 96%) in great yields (up to 95%).
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Jia-Rong Chen, Yuan-Yuan Lai, Hai-Hua Lu, Xu-Fan Wang, Wen-Jing Xiao,