| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5225444 | Tetrahedron | 2009 | 6 Pages |
Abstract
A series of pyrrolidine-pyridine base organocatalysts have been developed and 3a found to be a highly effective catalyst for the asymmetric Michael addition reactions of ketones to chalcones. The reaction generated the corresponding products 1, 5-diketones in excellent diastereoselectivities (up to >99:1 dr) and enantioselectivities (up to 100% ee).
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Da-Zhen Xu, Sen Shi, Yingjun Liu, Yongmei Wang,