| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5225475 | Tetrahedron | 2008 | 9 Pages |
Abstract
Total synthesis of pyranicin and its deoxygenated analogues was achieved using Cl2Pd(CH3CN)2 catalyzed diastereoselective cyclization of the allylic ester as the key step. The inhibitory activity of these compounds for mitochondrial NADH-ubiquinone oxidoreductase (complex I) was poorer than those of ordinary mono-THF acetogenins such as annonacin.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Shin-ichi Furuhata, Yasunao Hattori, Motonori Okajima, Hiroyuki Konno, Masato Abe, Hideto Miyoshi, Tetsuhisa Goto, Hidefumi Makabe,