Article ID Journal Published Year Pages File Type
5225754 Tetrahedron 2008 5 Pages PDF
Abstract

Five new dolastanes (1–5) were isolated from the brown alga Dilophus spiralis. The structural elucidation of the isolated compounds and the assignment of relative stereochemistry were based on analyses of their spectroscopic data. The structure proposed for 1 was confirmed by single crystal X-ray diffraction analysis, whereas its absolute stereochemistry was determined using the modified Mosher's method. The cytotoxicity of 1–4 was evaluated against seven cell lines.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry