| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5225787 | Tetrahedron | 2007 | 6 Pages |
Abstract
Imidazolines were prepared in one-pot operation from aldehydes and diamines through oxidation of aminal intermediates by NBS. This method could be applied to various aromatic and aliphatic aldehydes and N-nonsubstituted and N-monosubstituted 1,2-diamines. Furthermore, it was found that CH2Cl2 could be altered to TBME, a more environmentally friendly solvent, in the reaction using N-nonsubstituted 1,2-diamines. The reaction conditions were very mild and chemoselective.
Graphical abstractDownload full-size image
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Hiromichi Fujioka, Kenichi Murai, Ozora Kubo, Yusuke Ohba, Yasuyuki Kita,