Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5225802 | Tetrahedron | 2007 | 7 Pages |
Abstract
Lithium amides react with vinylferrocene in the presence of TMEDA to provide the corresponding (2-aminoethyl)ferrocenes in good to excellent yields. A range of secondary amines can be employed in this amidolithiation reaction, with cyclic derivatives affording particularly good yields of the 2-aminoethyl-substituted ferrocene product. This operationally simple procedure provides one of the most straightforward routes to this class of mono-substituted ferrocene.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Kévin M. Joly, Renate M. Gleixner, Simon M.E. Simpkins, Diane M. Coe, Liam R. Cox,