Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5225803 | Tetrahedron | 2007 | 8 Pages |
Abstract
The Suzuki-Miyaura-type cross-coupling reaction of potassium alkyltrifluoroborates with various alkenyl bromides in the presence of 10 mol % of PdCl2(dppf)·CH2Cl2 and 3.0 equiv of Cs2CO3 in aqueous toluene at 80 °C provided the desired compounds in 63-95% yields. A variety of functional groups in the potassium alkyltrifluoroborates were tolerated under the basic conditions.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Gary A. Molander, Jungyeob Ham, Dave G. Seapy,