| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5225815 | Tetrahedron | 2010 | 8 Pages |
Abstract
A simple method for one-pot sequential Heck/Suzuki coupling reactions of a range of substituted aryl dihalides has been described. The Pd(OAc)2/imidazolium system catalyzed double coupling reactions proceed without isolation of the intermediates giving unsymmetrically polysubstituted biphenyls in good to excellent yields. Further couplings of the resultant products bearing additional C-Cl bonds with substituted arylboronic acids or amines lead to unsymmetrical terphenyls and aminobiphenyl derivatives.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Xiaoming Zhang, Weilong Xie, Wanzhi Chen,