Article ID Journal Published Year Pages File Type
5225861 Tetrahedron 2009 7 Pages PDF
Abstract

A highly efficient method is described for the one-carbon homologation of aldehydes to carboxylic acid derivatives employing the reaction of a 1,1-bis-dimethylphosphonate derivative with the aldehyde and controlled acid hydrolysis of the derived α-phosphonoenamine intermediate.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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