Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5225861 | Tetrahedron | 2009 | 7 Pages |
Abstract
A highly efficient method is described for the one-carbon homologation of aldehydes to carboxylic acid derivatives employing the reaction of a 1,1-bis-dimethylphosphonate derivative with the aldehyde and controlled acid hydrolysis of the derived α-phosphonoenamine intermediate.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
James McNulty, Priyabrata Das,