Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5225994 | Tetrahedron | 2010 | 5 Pages |
Abstract
The asymmetric bioreduction of activated CC-bonds catalyzed by a single flavoprotein was achieved via direct hydrogen transfer from a sacrificial 2-enone or 1,4-dione as hydrogen donor without requirement of a nicotinamide cofactor. Due to its simplicity, this system has clear advantages over conventional FAD-recycling systems.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Clemens Stueckler, Tamara C. Reiter, Nina Baudendistel, Kurt Faber,