Article ID Journal Published Year Pages File Type
5225994 Tetrahedron 2010 5 Pages PDF
Abstract

The asymmetric bioreduction of activated CC-bonds catalyzed by a single flavoprotein was achieved via direct hydrogen transfer from a sacrificial 2-enone or 1,4-dione as hydrogen donor without requirement of a nicotinamide cofactor. Due to its simplicity, this system has clear advantages over conventional FAD-recycling systems.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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