Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5225999 | Tetrahedron | 2010 | 11 Pages |
Abstract
The addition of mono- and dianions of ethyl N-pivaloyl-3-aminocrotonate to substituted nitroarenes, followed by action of silylating or acylating agent, leads to 3-aminoquinoline carboxylic acid derivatives. Hydrolysis and decarboxylation of the latter, carried out efficiently under relatively mild conditions, afford 3-aminoquinolines diversely substituted in the benzo-fused ring.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Robert Bujok, Andrzej Kwast, Piotr Cmoch, Zbigniew Wróbel,