| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5226032 | Tetrahedron | 2009 | 5 Pages |
Abstract
Intramolecular Friedel-Crafts alkylation reaction of indoles catalyzed by trisoxazoline/copper(II) is described. This annulation provides an easy access to polycyclic indole derivatives with up to 90% ee in up to 99% yield.
Graphical abstractDownload full-size imageAn intramolecular Friedel-Crafts alkylation reaction of indoles has been developed and up to 90% ee is achieved in high to excellent yields by empolying trisoxazoline/copper(II) as a catalyst.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Jiao-Long Zhou, Meng-Chun Ye, Xiu-Li Sun, Yong Tang,