| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5226035 | Tetrahedron | 2009 | 9 Pages |
Abstract
A mild method was developed to synthesize 6-amino-2-phenolic-9-alkyl and 9-arylpurines. The new compounds were screened for antibacterial activity against Mycobacterium tuberculosis strain H37Rv. The 9-tolyl derivatives with a dimethylamino or a piperidine substituent in C6 and the 3-hydroxyphenyl or 4-hydroxyphenyl substituent in C2 were highly active against the bacilli.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Carla Correia, M. Alice Carvalho, M. Fernanda Proença,