| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5226194 | Tetrahedron | 2009 | 5 Pages |
Abstract
A feasible procedure of using methyl formate as cheap reagent for the conversion of aliphatic and aromatic amines into formamides with high yields is reported. The improved amine formylation method proceeds mainly at room temperature and in presence of bicyclic guanidines as catalysts. A verifiable key intermediate of outstanding formylating activity is generated from methyl formate and the catalyst in the reaction mixture.
Graphical abstractDownload full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Jens Deutsch, Reinhard Eckelt, Angela Köckritz, Andreas Martin,