Article ID Journal Published Year Pages File Type
5226237 Tetrahedron 2009 8 Pages PDF
Abstract

Thermal and microwave initiated cyclization of 2,4-disubstituted 6-arylethynylpyrimidine-5-carbaldehydes with tert-butylamine has been studied. A novel high-yielding preparation of 2,4-disubstituted 7-arylpyrido[4,3-d]pyrimidines has been developed. The intermediate compounds were isolated and possible mechanism of the reactions is discussed.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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