Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5226237 | Tetrahedron | 2009 | 8 Pages |
Abstract
Thermal and microwave initiated cyclization of 2,4-disubstituted 6-arylethynylpyrimidine-5-carbaldehydes with tert-butylamine has been studied. A novel high-yielding preparation of 2,4-disubstituted 7-arylpyrido[4,3-d]pyrimidines has been developed. The intermediate compounds were isolated and possible mechanism of the reactions is discussed.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Inga Cikotiene, Visvaldas Kairys, Rita Buksnaitiene, Marius Morkunas, Simonas Rudys, Algirdas Brukstus, Miguel X. Fernandes,