Article ID Journal Published Year Pages File Type
5226312 Tetrahedron 2006 14 Pages PDF
Abstract

The scope of the novel allenic Alder-ene reaction using Rh(I) and Ir(I) catalysts has been extended to differentially substituted 1,1,3-trisubstituted allenes. This allenyl substitution pattern can give three possible cross-conjugated triene products. The selectivity of this transformation can be controlled by varying reaction temperature, solvent, and catalyst. Progress toward the synthesis of ovalicin using this triene forming protocol is described.

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Physical Sciences and Engineering Chemistry Organic Chemistry
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