Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5226339 | Tetrahedron | 2008 | 9 Pages |
Abstract
In this paper, we describe a practical and efficient protocol for Sonogashira, Suzuki-Miyaura, and Mizoroki-Heck cross-coupling using a CBT system. The use of substrates with cycloalkane-soluble tags facilitates separation of the desired products and the homogeneous Pd catalyst via simple liquid-liquid extraction, thereby eliminating the need for a catalyst removal process.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Shokaku Kim, Keisuke Yamamoto, Kanako Hayashi, Kazuhiro Chiba,