Article ID Journal Published Year Pages File Type
5226548 Tetrahedron 2009 6 Pages PDF
Abstract

Highly enantioselective Michael reaction of acetone with a variety of nitroolefins catalyzed by N-[(1R,2R)-2-aminocyclohexyl]-N′-(2,3,4,6-tetra-O-acetyl-β-d-glucopyranosyl)-thiourea (1b) together with acetic acid is described. The Michael addition products were obtained in high yields (76-94%) and up to 96% ee.

Graphical abstractDownload full-size image

Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Authors
, , ,