Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5226548 | Tetrahedron | 2009 | 6 Pages |
Abstract
Highly enantioselective Michael reaction of acetone with a variety of nitroolefins catalyzed by N-[(1R,2R)-2-aminocyclohexyl]-Nâ²-(2,3,4,6-tetra-O-acetyl-β-d-glucopyranosyl)-thiourea (1b) together with acetic acid is described. The Michael addition products were obtained in high yields (76-94%) and up to 96% ee.
Graphical abstractDownload full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Qing Gu, Xing-Tao Guo, Xin-Yan Wu,