Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5226647 | Tetrahedron | 2006 | 7 Pages |
Abstract
Sch 642305 is a fungal nonanolide, which inhibits bacterial DNA primase and HIV-1 Tat transactivation. The enantioselective synthesis of Sch 642305 was succeeded starting from useful chiral building block via stereoselective dianion alkylation of β-ketosulfoxide and lactonization.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ken Ishigami, Ryo Katsuta, Hidenori Watanabe,