Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5226669 | Tetrahedron | 2006 | 8 Pages |
Abstract
Benzoxazoles 2 can be smoothly synthesized by treatment of starting materials of N-(2-hydroxyaryl) cyclopropyl amides 1 with PPh3/CCl4 in acetonitrile in good yields. When PPh3/CBr4/MS 4 à was used in the reaction system, the corresponding ring-expanding products 3 were obtained in moderate to good yields in acetonitrile at 80 °C. Using DCE as a solvent in this reaction, the corresponding 2-(3-chloropropyl)benzoxazoles 5 were obtained as major products.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Yong-Hua Yang, Min Shi,