| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5226713 | Tetrahedron | 2008 | 7 Pages |
Abstract
Terminal alkyne-containing phosphoramidite and solid support were prepared and used for the synthesis of 5â²- and 3â²-alkyne-modified oligonucleotides. The copper-catalyzed Huisgen [3+2] cycloaddition reaction in water-DMSO was used for the efficient preparation of perylene diimide-oligonucleotide conjugates suitable for constructing various types of PDI-modified DNA duplexes.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Alexey V. Ustinov, Veronika V. Dubnyakova, Vladimir A. Korshun,