Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5226769 | Tetrahedron | 2009 | 5 Pages |
Abstract
Various α-aryl nitriles have been prepared in excellent yield from the corresponding α-aryl alcohols employing 3 mol % of B(C6F5)3 (1) as Lewis acid catalyst and (CH3)3SiCN (TMSCN) as cyanide source. Cyano transfer from TMSCN to alcohol proceeds within short reaction time at rt. α-Aryl thiols also produce corresponding nitriles in good to excellent yield at reflux condition.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Gurusamy Rajagopal, Sung Soo Kim,