Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5226797 | Tetrahedron | 2006 | 9 Pages |
Abstract
The reaction between glutaric anhydride (1) and N-benzylidenebenzylamine (3) was studied in detail by 1H NMR spectroscopy under different reaction conditions. The major product was (±)-trans-1-benzyl-6-oxo-2-phenylpiperidine-3-carboxylic acid (2), which was converted into new substituted piperidin-2-ones via transformations of the carboxylic group. The final products are expected to possess pharmaceutical activities, and the relevant screenings are in course.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Nikola T. Burdzhiev, Elena R. Stanoeva,