Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5226823 | Tetrahedron | 2008 | 6 Pages |
Abstract
Highly reactive iodoalkenes (α-iodostyrene and α,αâ²-diiodo-1,4-divinylbenzene) were prepared and used as substrates in palladium-catalysed aminocarbonylation reaction. Regardless of the type of amine nucleophile the corresponding N-substituted phenylacrylamides have been formed chemoselectively in nearly quantitative yields. High isolated yields (up to 83%) have been achieved both with unfunctionalised simple amines and amino acid methyl esters under mild reaction conditions.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Attila Takács, Roland Farkas, László Kollár,