| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5226830 | Tetrahedron | 2008 | 7 Pages |
Abstract
Reaction of 2-fluoroaziridines with potassium alkynyltrifluoroborates in the presence of BF3·OEt2 leads to fluorinated propargyl amines in moderate to good yields. The reaction proceeds as an in situ isomerization of 2-fluoroaziridines to α-fluorinated imines, followed by the reaction of the imine with alkynyldifluoroborane, which is generated in situ from the potassium alkynyltrifluoroborates and BF3·OEt2.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Alexander S. Konev, Sara Stas, Mikhail S. Novikov, Alexander F. Khlebnikov, Kourosch Abbaspour Tehrani,