Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5226904 | Tetrahedron | 2009 | 7 Pages |
Abstract
Selective N-monoalkylation of aromatic amines with 1° and 2° alcohols and conversion of aromatic amines to amides are performed immediately and in excellent yields using triphenylphosphine (PPh3) and 2,3-dichloro-5,6-dicyanobenzoquinone (DDQ) in dichloromethane at room temperature. Symmetrical and unsymmetrical N,N-dialkylation of aromatic amines are also carried out in modest yield at room temperature by this reagent system.
Graphical abstractDownload full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Nasser Iranpoor, Habib Firouzabadi, Najmeh Nowrouzi, Dariush Khalili,