| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5226981 | Tetrahedron | 2007 | 9 Pages |
Abstract
Hydroarylation of propiolic acid derivatives with arenes in trifluoroacetic acid efficiently proceeded in the presence of PtCl2/AgOTf catalyst to give cis-cinnamic acid derivatives in good to high yields. This PtCl2/AgOTf-catalyzed reaction did not afford any 4-arylbuta-1,3-diene-1,3-dicarboxylic acid derivatives formed by Pd(OAc)2-catalyzed hydroarylation. The specific optimization of the catalytic hydroarylation and application to electron-rich arenes are reported.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Juzo Oyamada, Tsugio Kitamura,