Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5226985 | Tetrahedron | 2007 | 5 Pages |
Abstract
An efficient synthesis of the potent KDR kinase inhibitor 3-[5-[[4-(methylsulfonyl)-1-piperazinyl]methyl]-1H-indol-2-yl]quinoline-2-(1H)-one using a Sonogashira coupling-5-endo-dig-cyclization strategy is described.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Sanjay S. Palimkar, Vijaykumar S. More, P. Harish Kumar, Kumar V. Srinivasan,