Article ID Journal Published Year Pages File Type
5226985 Tetrahedron 2007 5 Pages PDF
Abstract

An efficient synthesis of the potent KDR kinase inhibitor 3-[5-[[4-(methylsulfonyl)-1-piperazinyl]methyl]-1H-indol-2-yl]quinoline-2-(1H)-one using a Sonogashira coupling-5-endo-dig-cyclization strategy is described.

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Physical Sciences and Engineering Chemistry Organic Chemistry
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