Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5227073 | Tetrahedron | 2007 | 8 Pages |
Abstract
A concise route to the anti-tumour natural product (â)-varitriol, together with its novel isomer (â)-3â²-epi-varitriol, is described using a Horner-Wadsworth-Emmons (HWE)/conjugate addition/Ramberg-Bäcklund sequence as the cornerstone. The flexibility of the synthetic route has been demonstrated by the preparation of novel varitriol analogues.
Graphical abstract
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Graeme D. McAllister, James E. Robinson, Richard J.K. Taylor,