Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5227490 | Tetrahedron | 2006 | 12 Pages |
Abstract
The synthesis of potassium aeshynomate and its non-natural stereomers was achieved using the Sharpless catalytic asymmetric dihydroxylation of (Z) or (E) vinylogous glycine as the key step. The resulting γ-amino α,β-dihydroxyester stereomer was deprotected and coupled with the caffeic acid to afford stereoselectively potassium aeshynomate or its stereomers. A detailed study of the NMR data of the different stereomers is reported that corrects the literature data.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Stéphanie Claudel, Tomasz Krzysztof Olszewski, Pierre Mutzenardt, Christie Aroulanda, Philippe Coutrot, Claude Grison,