Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5227557 | Tetrahedron | 2006 | 7 Pages |
Abstract
The preparation of oxazole-4-carboxamides and their subsequent thermal rearrangement to 5-aminooxazole-4-carboxylates is optimized in a high-speed microwave-assisted procedure. The reaction sequence is effective with a variety of substituted oxazoles, and produces products in good yield and high purity.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
M. Brad Nolt, Mark A. Smiley, Sandor L. Varga, Ray T. McClain, Scott E. Wolkenberg, Craig W. Lindsley,