Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5227781 | Tetrahedron | 2008 | 7 Pages |
Abstract
Two pentasaccharides containing a common tetrasaccharide (lacto-N-neotetraose) core, and d-galactosamine and N-acetyl neuraminic acid in the non-reducing ends, respectively, corresponding to the lipooligosaccharides of Neisseria gonorrhoeae and Neisseria meningitidis were synthesized in a very concise manner from a common trisaccharide derivative using minimum number of steps. Thioglycosides and glycosyl trichloroacetimidate have been used as glycosyl donors for glycosylations and yields were excellent in every step.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Pintu Kumar Mandal, Anup Kumar Misra,