Article ID Journal Published Year Pages File Type
5227781 Tetrahedron 2008 7 Pages PDF
Abstract

Two pentasaccharides containing a common tetrasaccharide (lacto-N-neotetraose) core, and d-galactosamine and N-acetyl neuraminic acid in the non-reducing ends, respectively, corresponding to the lipooligosaccharides of Neisseria gonorrhoeae and Neisseria meningitidis were synthesized in a very concise manner from a common trisaccharide derivative using minimum number of steps. Thioglycosides and glycosyl trichloroacetimidate have been used as glycosyl donors for glycosylations and yields were excellent in every step.

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Physical Sciences and Engineering Chemistry Organic Chemistry
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