Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5227854 | Tetrahedron | 2007 | 8 Pages |
Abstract
Copper(I) triflate acts as an efficient stoichiometric reagent for the homo-coupling of aryldiazonium salts bearing electron-withdrawing group(s), to yield symmetrical biaryls in acetonitrile under mild reaction conditions. Aryldiazonium salts bearing electron-donating groups undergo the reaction by using catalytic amounts of a copper complex prepared in situ from copper(II) triflate and 2,2â²-bipyridine with metallic copper as an ultimate reductant.
Graphical abstract(i) 1.5 equiv CuOTf; MeCN; 0 °C-rt; overnight; R=EWG(s); (ii) 20 mol % Cu(OTf)2, bpy; 3 equiv Cu; MeCN; rt; overnight; R=H or EDG(s); 15 examples; yields: 7-96%.Download full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ivica Cepanec, Mladen LitviÄ, Josipa UdikoviÄ, Ivan PogoreliÄ, Marija LovriÄ,