| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5227943 | Tetrahedron | 2006 | 13 Pages |
Abstract
Routes were investigated for the synthesis of cicerfuran, a hydroxylated benzofuran from wild chickpea implicated in resistance to Fusarium wilt, and some of its analogues. A novel method is described for the synthesis of oxygenated benzofurans by epoxidation and cyclisation of 2â²-hydroxystilbenes. The stilbene intermediates required could be synthesised by palladium-catalysed coupling of styrenes with mono-oxygenated aryl halides but not with di-oxygenated aryl halides. Stilbenes corresponding to the latter were synthesised by Wittig reactions.
Graphical AbstractDownload full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Shazia N. Aslam, Philip C. Stevenson, Sara J. Phythian, Nigel C. Veitch, David R. Hall,