Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5228095 | Tetrahedron | 2008 | 9 Pages |
Abstract
A facile synthesis of substituted alkylidene cyclopentenes through a palladium catalyzed ring opening of fulvene derived bicyclic hydrazines with various organometallic reagents is described. The products are versatile synthons with multiple points for functionalization and can be used in the synthesis of a number of biologically active molecules.
Graphical abstractPalladium/Lewis acid catalyzed ring opening of fulvene derived bicyclic hydrazines with various organometallic reagents leading to the stereoselective synthesis of substituted alkylidene cyclopentenes is described.Download full-size image
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
S. Anas, V.S. Sajisha, Jubi John, Nayana Joseph, Sholly Clair George, K.V. Radhakrishnan,