| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5228221 | Tetrahedron | 2007 | 6 Pages |
Abstract
Synthesis of novel 4,5-dihydro-1H-1,4-naphthoquino[b]-benzo[e][1,4]diazepine derivatives via Pictet-Spengler cyclization is reported. Reaction of 2,3-diamino-naphthoquinones with aldehydes in the presence of BF3·Et2O gives benzodiazepine-naphthoquinones in good yields.
Graphical abstractSynthesis of novel benzodiazepine derivatives of 1,4-naphthoquinones via Pictet-Spengler reaction is reported. Reaction of diaminonaphthoquinones with aldehydes in the presence of BF3·Et2O gives benzodiazepine-naphthoquinones in good yields.Download full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
![Synthesis of novel substituted naphthoquino[b]-benzo[e][1,4]diazepines via Pictet-Spengler cyclization](/preview/png/5228221.png "First Page Preview: Synthesis of novel substituted naphthoquino[b]-benzo[e][1,4]diazepines via Pictet-Spengler cyclization")
Authors
Xiao Lei Wang, Xiu Fang Zheng, Ren He Liu, John Reiner, Jun Biao Chang,