| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5228222 | Tetrahedron | 2007 | 13 Pages |
Abstract
Cholesterol plays the role of membrane reinforcer in eukaryotes, whereas hopanoids play the same role in bacteria. Which components could have reinforced 'primitive' membranes? We describe here an efficient biomimetic synthesis of bi- and tri-cyclopolyprenols and demonstrate that these compounds reinforce the membranes of polyprenyl phosphate, which we speculated as 'primitive' membranes.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Nigel Ribeiro, Stéphane Streiff, Denis Heissler, Mourad Elhabiri, Anne Marie Albrecht-Gary, Michiko Atsumi, Mari Gotoh, Laurent Désaubry, Yoichi Nakatani, Guy Ourisson,