Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5228277 | Tetrahedron | 2005 | 15 Pages |
Abstract
The synthesis of polyfunctionalized fused aromatic carbo- and heterocycles from aryl iodides and bromoenoates via a tandem palladium-catalyzed aromatic substitution intramolecular Heck sequence is reported. Using Pd(OAc)2 and tri-2-furylphosphine in the presence of norbornene and Cs2CO3 in CH3CN at 85 °C gave a variety of functionalized bi- and tricyclic fused aromatic rings in good yield.
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Authors
Dino Alberico, Jean-François Paquin, Mark Lautens,